Multiple cranial nerve palsies following COVID-19 vaccination-Case report

© 2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd..

BACKGROUND: The novel COVID-19 vaccines have side effects that require efficient and close monitoring.

AIMS OF THE STUDY: To examine whether the Pfizer-BioNTech vaccine is associated with multiple cranial neuropathy.

METHODS: We report the case of a 29-year-old male patient with no notable history who presented with left oculomotor, abducens, trigeminal and facial palsies 6 days after receiving the first dose of the Pfizer-BioNTech COVID-19 vaccine.

RESULTS: Gadolinium-enhanced MRI of the brain revealed enhancement in the left facial, trigeminal and oculomotor nerves, which persisted upon repeated examination. The cerebrospinal fluid analysis showed no sign of inflammation, both initially and after 1 month from the start of the patient's symptoms. Other causes were excluded by laboratory tests. The patient received high doses of corticosteroids, with improvement of symptoms.

CONCLUSIONS: In our case, the most probable etiology of the patient's multiple cranial neuropathy is the Pfizer-BioNTech vaccine, which highlights the need for prolonged surveillance of COVID-19 vaccine neurological complications.

Media Type:

Electronic Article

Year of Publication:

2022

Contained In:

Acta neurologica Scandinavica - Vol. 145, No. 2 (2022), p. 257-259

Language:

English

Contributors:

Manea, Maria Mirabela
Dragoș, Dorin
Enache, Iulia
Sirbu, Adrian George
Tuta, Sorin

Urls:

Volltext

Keywords: Schlagworte
Notes:

Date Completed 04.01.2022

Date Revised 04.01.2022

published: Print-Electronic

Citation Status MEDLINE

Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Physical Description:

Online-Ressource

doi:

10.1111/ane.13548

PMID:

34725821

PPN (Catalogue-ID):

NLM333787420