Symptomatic COVID-19 infections in outpatient image-guided corticosteroid injection patients during the lockdown phase

BACKGROUND: Musculoskeletal pain is a debilitating problem treated with image-guided corticosteroid injections. During the COVID-19 pandemic, multiple societies issued caution statements because of the unknown effect of corticosteroids on the patient's immune system. The purpose is to determine if image-guided corticosteroid injections administered during the COVID-19 lockdown phase were associated with a higher infection rate compared to the general population.

MATERIALS AND METHODS: In a prospective study, patients undergoing image-guided corticosteroid injections for pain management during the lockdown phase between April 15 and May 22, 2020, were enrolled. One month after the injection, patients were surveyed by telephone for any COVID-19-related symptoms, and the electronic medical record (EMR) was reviewed for symptoms and test results.

RESULTS: Seventy-one subjects were recruited, 31 (44%) females, 40 (56%) males, ages 58 ± 17 (20-92) years. Follow-up was available in 66 (93%) of subjects, 60 (91%) by phone survey and EMR, 6 (9%) by EMR only, 45 ± 22 (19-83) days after injection. One (1/66, 1.52%; 95% CI 0.04-8.2%) 25-year-old male subject developed symptomatic infection 19 days after a tibiotalar injection. The prevalence of COVID-19 cases in the state of Massachusetts was 0.91% (62,726/6,892,503) during the study period. There was no significant difference in the rate of occurrence of new cases of COVID-19 infection between the corticosteroid injection group and the general population (p = 0.44).

CONCLUSION: Image-guided corticosteroid injections for pain management performed during the lockdown phase of the COVID-19 pandemic were not associated with a higher infection rate compared to the general population.

Media Type:

Electronic Article

Year of Publication:

2021

Contained In:

Skeletal radiology - Vol. 50, No. 6 (2021), p. 1117-1123

Language:

English

Contributors:

Chang, Connie Y
Prabhakar, Anand
Staffa, Steven J
Husseini, Jad S
Kheterpal, Arvin B
Simeone, F Joseph
Bredella, Miriam A

Urls:

Volltext

Keywords:

*Pain Management
Adrenal Cortex Hormones
Adult
Aged
COVID
COVID-19
Corticosteroid
Female
Humans
Image guidance
Infection
Injection
Injections
Journal Article
Male
Middle Aged
Outpatients
Pandemics
Prospective Studies

Notes:

Date Completed 23.04.2021

Date Revised 01.06.2021

published: Print-Electronic

Citation Status MEDLINE

Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Physical Description:

Online-Ressource

doi:

10.1007/s00256-020-03656-w

PMID:

33108512

PPN (Catalogue-ID):

NLM31775095X