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Bronchopleural fistula development in the setting of novel therapies for acute respiratory distress syndrome in SARS-CoV-2 pneumonia

Published by Elsevier Inc. on behalf of University of Washington.

COVID-19 pneumonia has demonstrated a wide spectrum of clinical presentations that has yet to be completely uncovered. We discuss the case of a 49-year-old male who presented to the emergency department with fever, cough, and shortness of breath. Initial chest X-ray suggested viral pneumonia that was confirmed to be due to COVID-19. He was treated with empiric antibiotics, antiviral therapy, high-dose glucocorticoids, and interleukin antagonists. Two weeks into the patient's hospital course, he rapidly decompensated with subsequent chest X-ray and CT chest confirming tension pneumothorax with bronchopleural fistula. Intraoperative samples of the necrotic empyema identified mucormycosis invading the lung parenchyma with follow-up microbiology results confirming Rhizopus species. In this case report, we explore the possibility that the patient's immunocompromised state may have contributed to the patient's development of mucormycosis and subsequent development of bronchopleural fistula

Year of Publication: 2020
Contained in: Radiology case reports Vol. 15, No. 11 (2020), p. 2378-2381
All journal articles: Search for all articles in this journal
Language: English
Contributors: Placik, Daniel A | Author
Taylor, Wesley L
Wnuk, Nathan M
Full text access:
Electronic availability is being checked...
Links: Full Text (dx.doi.org)
Keywords: COVID
Case Reports
Dexamethasone
Mucormycosis
Pneumonia
Remdesivir
Tocilizumab
ISSN: 1930-0433
Note: Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Notes: Date Revised 01.10.2020
published: Print-Electronic
Citation Status PubMed-not-MEDLINE
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
PMID:
    32983308
Physical Description: Online-Ressource
ID (e.g. DOI, URN): 10.1016/j.radcr.2020.09.026
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