The Quality of Life of Patients with Suspected Lung Cancer before and after Bronchoscopy and the Effect of Mirtazapine on the Depressive Status

Objective Patients with suspected lung cancer often experience adverse side effects such as anxiety, depression, and a decreased appetite. These side effects influence the patients' quality of life and their ability to make decisions concerning appropriate treatment. This study examined the psychological status and quality of life of patients with suspected lung cancer before and after bronchoscopy treatment and evaluated the effect of mirtazapine prescribed to patients with depression. Methods To assess patient characteristics (e.g. age, gender, and medical history), a questionnaire including the Hospital Anxiety and Depression Scale - Japanese version and the Functional Assessment of Cancer Therapy-L was administered. Patients Forty-three patients admitted for bronchoscopy treatment between May 2017 and April 2018 were included. Results The results showed that patients with depression reported a worse quality of life than those without depression. Compared with no medication, the administration of mirtazapine alleviated depressive symptoms. Furthermore, the patients' depressive status was affected by their physical symptoms, including coughing, tightness of chest, and dyspnea. Conclusion Our results emphasize the importance of detecting depression in the early stages of a cancer diagnosis and have significant implications concerning pharmacological intervention in patients with cancer displaying signs of depression.

Media Type:

Electronic Article

Year of Publication:

2020

Contained In:

Internal medicine (Tokyo, Japan) - Vol. 59, No. 13 (2020), p. 1605-1610

Language:

English

Contributors:

Kaneko, Yoshiko
Mouri, Takako
Seto, Yurie
Nishioka, Naoya
Yoshimura, Akihiro
Yamamoto, Chie
Harita, Sachi
Chihara, Yusuke
Tamiya, Nobuyo
Yamada, Tadaaki
Uchino, Junji
Takayama, Koichi

Urls:

Volltext

Keywords:

*Quality of Life
A051Q2099Q
Adult
Aged
Antidepressive Agents
Bronchoscopy
Depression
Female
Humans
Journal Article
Lung Neoplasms
Lung cancer
Male
Middle Aged
Mirtazapine
Quality of life
Surveys and Questionnaires

Notes:

Date Completed 16.10.2020

Date Revised 16.10.2020

published: Print-Electronic

Citation Status MEDLINE

Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Physical Description:

Online-Ressource

doi:

10.2169/internalmedicine.4341-19

PMID:

32612064

PPN (Catalogue-ID):

NLM312808399