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Elderly at time of COronaVIrus disease 2019 (COVID-19) : possible role of immunosenescence and malnutrition

The unprecedented COVID-19 pandemic is rapidly and unpredictably evolving and the majority of deaths are occurring in older people. A partial description of the magnitude of the scenario is provided by numbers and statistics, which probably underestimate the ongoing tragedy. In the present opinion paper, we have focused our attention on the evidence of the relationship among malnutrition, immunosenescence, and the higher morbidity and mortality in elderly patients. In particular, we propose the intriguing hypothesis that correction of nutritional deficits may attenuate the age-dependent alterations of the innate and adaptive immune system which participate in the increased susceptibility and worse outcome observed in the elderly COVID-19 patients

Year of Publication: 2020
Contained in: GeroScience Vol. 42, No. 4 (2020), p. 1089-1092
All journal articles: Search for all articles in this journal
Language: English
Contributors: Bencivenga, Leonardo | Author
Rengo, Giuseppe
Varricchi, Gilda
Full text access:
Electronic availability is being checked...
Links: Full Text (dx.doi.org)
Keywords: COVID-19
Elderly
Immunosenescence
Journal Article
Malnutrition
Pandemic
ISSN: 2509-2723
Note: Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Notes: Date Revised 04.08.2020
published: Print-Electronic
Citation Status In-Process
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
PMID:
    32578073
Physical Description: Online-Ressource
ID (e.g. DOI, URN): 10.1007/s11357-020-00218-9
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